ABSTRACT
Lipoleiomyoma of the uterus [LLU] is an extremely rare, benign, uterine tumour. This rare disease was unknown for a long time. Their histogenesis remains controversial. To describe the clinical and pathological aspects of uterine lipoleiomyoma and to try to specify, by an immunohistochemical study, its degenerative or tumoral nature. 7 cases of LLU were identified represented by 2 pure Lipoma and 5 Lipoleiomyoma. We performed an immunohistochemical study including anti-vimentin, anti-smooth muscle actin, anti PS-100, anti-desmin, anti-factor VIII and anti-HMB- 45. The results were correlated with the pathogenesis of this lesion. Immunohistochemical analysis showed an expression of PS 100 only in lipocytes whereas leiomyomatous cells express only smooth muscle actin. Our study supports the benign tumoral nature of the fatty uterine lesions. Lipoleiomyomatous cells may originate from the transformation of a totipotent mesenchymal cell and not from a degenerative process
ABSTRACT
Sclerosing stromal tumor [SST] is an uncommon benign tumor of the ovary, representing 2-6% of all stromal ovarian tumors. Comparatively to other fibrothecals tumors, SST is distinct by particular clinical and histological features. A case of SST occurring in 15-year-old female and review of the literature are described in the present article
ABSTRACT
Little information regarding synchronous gastric cancer associated with hepatocellular carcinoma is available and has been sporadically reported. We report a new case of 60 years old patient operated for gastric carcinoma. The radiological investigations revealed a hepatic nodule which correspond to a hepatocellular carcinoma on histological examination. The aim of this study is to clarify the clinicopathologic and therapeutic features of this association
Subject(s)
Humans , Male , Carcinoma, Hepatocellular/diagnosis , Liver Neoplasms , Neoplasms, Multiple Primary/diagnosisABSTRACT
Primary intestinal T-celI lymphomas account for about 5% of all primary gastrointestinal lymphomas and are mostly associated with coeliac disease. Intestinal lymphomas are usually discovered during the 4 th to5 th decade and constitute an exceptional complication of coeliac disease. This lymphoma is generally a high grade pleomorphic cell lymphoma with large cells. Our case concerned a 30 year old woman with a history of coeliac disease who developed a gastro-enteromesenteric lymphoma. Anatomopathological and immunohistochemical analysis showed an enteropathy associated T-cell lymphoma. We suggest that patients with coeliac disease unresponsive to a gluten free diet or with deteriorating clinical condition be investigated for complications such as enteropathy associated T-cell lymphoma. It is also important to avoid this complication by detecting asymptomatic form of coeliac disease that needs a gluten-free diet
Subject(s)
Humans , Female , Intestinal Neoplasms , Celiac Disease/complicationsABSTRACT
Visceral localizations in Hodgkin disease are well known and well documented in Ann Arbor Classification. They imply a relatively severe prognosis. Liver, lung and osteomedullar involvements are most frequent. Skeletal muscle involvement seems less frequent, but may be underdocumented. We describe here the case of a Hodgkin's disease evidenced through muscular localization in a 50 year old patient, with negative extension appraisal and a favorable evolution under polychemotherapy. This case is to be linked to the few descriptions already published and brings forth several question: the real frequency of such localization, its pathogenicity and its significance for the prognosis are yet unclear